The Input Impedance of this module is very high and is symmetric. This circuit can be used for strain gauges and for four wire measurements. If inputs are in mV use OP07. The merit is that it uses only 2 OpAmps yet has high differential Input Impedance.
Dual Differential Amp - Op-Amp Designs
The Outputs of Opamps are low impedance but still have limits they cannot drive more than a few mA of Current into the Load. If low ohmic value loads are to be applied use external transistors as amplifiers. If inputs Vn-Vp are floating, outputs may be random or oscillating, it is good to have a bias network of 10M resistors to a potential even zero or common, this enables some Vout when input floats.

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